In his cell, Padre Pio prayed and offered up his suffering. It was here that his life drew to a close and he was able to return to the house of the Almighty.

We can see: fingerless gloves lying on a table to the left; some white socks with blood stains on them; a piece of bandage used on his chest wound; a casket containing blood clots from the stigmata; books on spiritual subjects; a folding chair and the handkerchief with which Padre Pio blessed the pilgrims from his window (over the washbasin, on the right).
A phosphorescent statue of the Madonna, small holy pictures, two alarm clocks, a watch and a copy of the Life of God's Servant, Genoveffa de Troia can be seen in a small bedside cabinet.

The slippers worn by Padre Pio to the last hour of his death are in a casket. Next to the small armchair there is a small table with a few mementoes: a friar's cord, a rosary, a relic of the Holy Cross, some medals, as well as sweets he would give to children and a box containing the snuff he would offer to his friends.
A proper washbasin, situated in the hollow of the blessing window, has replaced the basin which stood on a wrought iron trestle. The small armchair in the cell was the 'seat of divine and human wisdom' where Padre Pio would fall deep into meditation, prepare for Mass or listen to the hardships and joys of children in faith, and where he finally gave himself over to death in preparation for his way to Heaven.