9 October - At the request of the General of the Capuchins, Padre Venanzio from Lisle-en-Rigault, Padre Pio underwent in-depth medical examinations conducted by Dr Giorgio Festa.
1923 - 17 June - Padre Pio was debarred from saying Mass in public or replying to any of the letters arriving at the monastery in San Giovanni Rotondo.
25 June - A popular revolt broke out on the afternoon of the day when Padre Pio first said Mass in a private chapel.
26 June - Padre Pio resumed saying Masses in the church.
8 August - Padre Pio was ordered to move to Ancona.
17 August - Worried by the restlessness of the crowds, the ecclesiastical authorities suspended this order.
1925 - 22 April - Resenting the restrictions placed on Padre Pio's confessional duties, the faithful throughout the country were again in a state of turmoil.
1933 - 16 July - Padre Pio resumed saying Masses in public following a two-year suspension.
1940 - 9 January - Work was started on Padre Pio's "Grand Earthly Undertaking", namely the building of his "House for the Relief of Suffering ".
1956 - 5 May - The House for the Relief of Suffering was officially opened.
1968 - 22 September - Padre Pio said Mass at 5 a.m. as usual. This was to be his last celebration of the Eucharist.
23 September - Padre Pio died at 02.30, his last words being "Jesus, Mary! Jesus, Mary!"
26 September - Over a hundred thousand people attended his funeral.
27 September - The crypt containing Padre Pio's body was opened to the public and was visited by droves of pilgrims over the years.
1983 - 20 March - The official enquiry into Padre Pio's case was opened in San Giovanni Rotondo.
1987 - 23 May - The Holy Father, John Paul II, made a pilgrimage to San Giovanni Rotondo and prayed at Padre Pio's tomb.
1990 - 21 January - The beatification process was completed.
1997 - April - Padre Pio was declared Venerable.
1999 - 2 May - Padre Pio of Pietrelcina was officially beatified by John Paul II.